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Science News

Parkinson’s Foundation researchers and other scientists worldwide make continual advances in understanding Parkinson’s disease (PD) with revolutionary research. We monitor it all in our effort to improving care and advance research toward a cure. Browse our collection here:

New Evidence Links Traumatic Brain Injury with Parkinson’s
Wednesday, July 13, 2016

A new study finds that traumatic brain injury from a blow to the head, with loss of consciousness, may increase a person’s risk of developing Parkinson’s disease (PD) later in life. The results appear in the July 11 online edition of JAMA Neurology. The researchers did not find an association between head injury and Alzheimer’s disease.

Cancer Drug Shows Evidence of Safety for Parkinson’s
Monday, July 11, 2016

Nilotinib, a drug already approved for treatment of leukemia and with potential for treating Parkinson’s disease (PD) may be safe to use experimentally in PD, according to the results of a small, phase 1 clinical trial. The study appears in the July 11 online edition of the Journal of Parkinson’s Disease.

Study Pinpoints Cause of Dyskinesias from Cell Transplant Therapy for Parkinson’s
Thursday, June 30, 2016

Researchers have discovered a potential mechanism underlying dyskinesias among some people with Parkinson’s disease (PD) who have been treated with cell replacement therapies. This discovery is particularly important, as there are several trials being planned to test cell replacement therapies for PD. The results provide a potential way of developing cell therapies that benefit people with PD without causing dyskinesia.

New Gene Discovered That Causes Inherited Parkinson’s Disease
Tuesday, June 28, 2016

Scientists have identified a new gene, called TMEM230, that causes Parkinson’s disease (PD) when just one of a person’s two copies of the gene is mutated. They also determined that the gene normally plays a role in packaging the chemical messenger dopamine for storage and transport within brain cells. The research appears in the June 6 online edition of Nature Genetics.

Is Parkinson’s Disease on the Rise?
Monday, June 20, 2016

A new study finds that the number of new cases per year of Parkinson’s disease (PD), and related diseases known as parkinsonisms, may have increased over a 30-year period. A possible explanation lies in the dramatic decline in cigarette smoking in recent decades. The research appears in the June 20 online edition of JAMA Neurology.

Study Questions Physical Therapy for Early and Moderate-Stage Parkinson’s
Wednesday, June 1, 2016

People with early and moderate-stage Parkinson’s disease (PD) with no clear need for physical or occupational therapy who received a “low-dose” program did not see an improvement in their ability to carry out daily activities, according to research published on January 19 in the online edition of JAMA Neurology. The authors conclude that more structured and intensive physical and occupational therapy should be tested fo

Inhaled Levodopa Provides Relief for “Off” Periods
Friday, May 20, 2016

According to a new study, an experimental inhaled form of levodopa can rapidly relieve Parkinson’s disease (PD) motor symptoms during “off” periods, the times when symptoms return in between regular doses of oral levodopa. The results appear in the April 19 online edition of Movement Disorders.

FDA Approves Nuplazid™ for Treatment of Psychosis in Parkinson’s
Tuesday, May 3, 2016

The Parkinson’s Disease Foundation (PDF) alerts the community that pimavanserin (Nuplazid™) has been approved by the US Food and Drug Administration (FDA) for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. The drug’s manufacturer, Acadia Pharmaceuticals Inc., announced the approval on April 29.

Stem Cell Therapies for Parkinson’s: Five Questions to Ask Before Participating in a Clinical Trial
Tuesday, April 26, 2016

How can people with Parkinson’s disease (PD) assess the safety of clinical trialsfor stem cell therapies? After years of study, stem cell treatments, which involve transplanting cells to replace the brain cells lost in PD are being tested in clinicaltrials around the world. But the history of these therapies has been fraught with confusion and disappointment.

Progress Toward Understanding Fatigue in Parkinson’s Disease
Thursday, March 24, 2016

The results of the Parkinson’s Disease Foundation’s (PDF) Conference on Fatigue, the first meeting supported by our Community Choice Research Awards, have now been published in the online editions of npj Parkinson’s Disease on January 14 and Movement Disorders on February 16.

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