Call Our HELPLINE: 1-800-4PD-INFO (473-4636)

Statement on Nuplazid Drug

On 4/9/18, CNN published an article on the FDA-approved drug, Nuplazid, used to treat hallucinations and psychosis A broad medical term used to describe a loss of contact with reality that involves hallucinations and/or delusions. in Parkinson’s disease. The article investigates FDA data showing the number of reported deaths with people taking Nuplazid. Nuplazid was approved by the FDA in 2016 and is manufactured by Acadia Pharmaceuticals.

The Parkinson’s Foundation is closely monitoring the recent reports on Nuplazid. At this time, we are recommending that patients on this drug consult with their neurologists about the risks and benefits of the treatment. The FDA will continue to monitor the drug’s use and safety, but they have not identified a specific safety issue that isn’t already described in the drug’s label. 

Parkinson’s disease psychosis is typically seen in advanced stages of Parkinson’s disease involving elderly patients. Treating Parkinson’s disease psychosis is a multi-step process that begins with talking to your health care team. They will follow a series of steps to figure out how best to address symptoms. For more information on this topic, please call our toll-free Helpline at 1-800-4PD-INFO (473-4636). 

Please report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088. You can also call ACADIA Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

For more information about Psychosis and Parkinson’s Disease:

Listen to our podcast

Read our recent blog article

Read more in our free book, "Psychosis: A Mind Guide to Parkinson's Disease"

Watch our Expert Briefings: Parkinson's Disease Psychosis: Hallucinations, Delusions and Paranoia

Tuesday, April 10, 2018
National Parkinson Foundation Expands Expert Care Network in Italy
Wednesday, November 2, 2016

MIAMI — The National Parkinson Foundation (NPF), a division of the Parkinson’s Foundation, announced today a new partnership with the Fresco Institute Italia to improve the quality of Parkinson’s care in Italy. The NPF Center of Excellence global network embodies the world’s leading Parkinson’s specialists focused on changing the course of Parkinson’s disease (PD). 

U.S. Senator Cory Booker Serves as Grand Marshal of Moving Day® Miami
Tuesday, November 1, 2016

MIAMI — The National Parkinson Foundation is pleased to announce that U.S. Senator Cory Booker (NJ) will serve as the Grand Marshal of the 5th Annual Moving Day Miami, the foundation’s walk to raise awareness of Parkinson’s disease in South Florida. The event, presented by Terranova Corporation, begins at 9 a.m.

PDF Champion to Host 14th Annual Music for Parkinson’s Research Concert on Sunday, November 13 in Rye, NY
Monday, October 24, 2016

White Plains, NY, clinical psychologist David Eger, Ph.D., is on a mission to help end Parkinson’s through music.  The 14th annual Music for Parkinson’s Research concert, which benefits the Parkinson’s Disease Foundation’s (PDF) research programs, will take place on Sunday, November 13 at 3:30 PM at the Congregation Emanu-El in Rye, NY.  The chamber music concert is organized by Dr.

PDF Recognizes Scholars of Edmond J. Safra Visiting Nurse Faculty Program for Outstanding Efforts in Nursing Education
Wednesday, October 19, 2016

The Parkinson’s Disease Foundation (PDF) congratulates Laura Kelly, Ph.D., R.N., A.N.P.-C., and Cheryl Leiningen, D.N.P., R.N., A.N.P.-C., Scholars of The Edmond J. Safra Visiting Nurse Faculty Program at PDF and 2016 recipients of the program’s annual Alumni Award for outstanding work in nursing education. Drs.

Patient Access Network Foundation and the National Parkinson Foundation Announce New Alliance to Provide Support for People Living With Parkinson’s Disease
Thursday, October 20, 2016

Washington, DC — The Patient Access Network (PAN) Foundation and the National Parkinson Foundation (NPF), a division of the Parkinson’s Foundation, today announced they are launching a new alliance to offer a broad range of support for people living with Parkinson’s disease.

The Parkinson’s Foundation Joins Global Community at 4th World Parkinson Congress in Portland, OR
Tuesday, September 20, 2016

New York, NY & Miami, FL —  The Parkinson's Foundation, recently formed by the merger of the National Parkinson Foundation® (NPF®) and the Parkinson’s Disease Foundation® (PDF®), is pleased to join the global Parkinson’s community this week at the 4th World Parkinson Congress (WPC) in Portland, OR.  The Parkinson’s Foundation offers interactive programs to encourage the Congress’ 4,000 delegates and those partici

National Parkinson Foundation Hosts Caregiver Summit
Monday, September 12, 2016

MIAMI — The National Parkinson Foundation (NPF), a division of the Parkinson’s Foundation, will be hosting the first-ever Caregiver Summit, geared specifically toward caregivers of people living with Parkinson’s disease (PD).

Refuting Claims Regarding Presidential Nominee Hillary Clinton and Parkinson’s Disease
Friday, September 9, 2016

The National Parkinson Foundation has received several questions about whether Hillary Clinton has Parkinson's disease (PD).

The allegations that Hillary Clinton suffers from Parkinson's disease have been reviewed by NPF's National Medical Director, Michael S. Okun, MD, and by others from NPF's Centers of Excellence network and been unanimously dismissed by every Parkinson's expert who has weighed in.

Parkinson's Disease Foundation Invests in Next Generation of Physical Therapy Leaders
Thursday, August 4, 2016

PDF Launches Innovative Pilot Training Program for Physical Therapy Educators

The Parkinson's Disease Foundation® (PDF®) is pleased to announce the launch of the Physical Therapy Faculty Program to improve care for the nearly one million people in the United States living with Parkinson’s disease. The pilot program launched this week in Boston, MA.

National Parkinson Foundation (NPF) and the Parkinson’s Disease Foundation (PDF) Complete Merger to Form the Parkinson’s Foundation
Monday, August 1, 2016

New York and Miami, August 1, 2016—The Boards of Directors of the National Parkinson Foundation (NPF) and the Parkinson's Disease Foundation (PDF) announced today that they have finalized the merger of the two non-profit organizations. The organization will operate as the Parkinson's Foundation with offices in New York City and Miami.

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