Parkinson's Foundation: Better Lives. Together.
Call Our HELPLINE: 1-800-4PD-INFO (473-4636)

Statement on Nuplazid Drug

On 4/9/18, CNN published an article on the FDA-approved drug, Nuplazid, used to treat hallucinations and psychosis in Parkinson’s disease. The article investigates FDA data showing the number of reported deaths with people taking Nuplazid. Nuplazid was approved by the FDA in 2016 and is manufactured by Acadia Pharmaceuticals.

The Parkinson’s Foundation is closely monitoring the recent reports on Nuplazid. At this time, we are recommending that patients on this drug consult with their neurologists about the risks and benefits of the treatment. The FDA will continue to monitor the drug’s use and safety, but they have not identified a specific safety issue that isn’t already described in the drug’s label. 

Parkinson’s disease psychosis is typically seen in advanced stages of Parkinson’s disease involving elderly patients. Treating Parkinson’s disease psychosis is a multi-step process that begins with talking to your health care team. They will follow a series of steps to figure out how best to address symptoms. For more information on this topic, please call our toll-free Helpline at 1-800-4PD-INFO (473-4636). 

Please report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088. You can also call ACADIA Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

For more information about Psychosis and Parkinson’s Disease:

Listen to our podcast

Read our recent blog article

Read more in our free book, "Psychosis: A Mind Guide to Parkinson's Disease"

Watch our Expert Briefings: Parkinson's Disease Psychosis: Hallucinations, Delusions and Paranoia

Tuesday, April 10, 2018
Connect.Parkinson Study Completes Enrollment
Friday, May 29, 2015

The National Parkinson Foundation Removes Barriers to Expert Parkinson’s Care Through Telemedicine

Afghanistan Veteran, PDF Champion to Complete Luxembourg IRONMAN for Parkinson’s Research on Saturday, June 20
Friday, May 29, 2015

US Army First Lieutenant Ashley Murray, a Piscataway, NJ, native, is running, biking and swimming to fight for a future without Parkinson’s disease. First Lt. Murray, an Afghanistan veteran who is currently stationed in Germany, will complete the Ergo IRONMAN 70.3 Luxembourg triathlon on Saturday, June 20 to raise funds for the Parkinson’s Disease Foundation (PDF).

Bal du Printemps Honors Supporters, Raises $460,000 for Research
Thursday, May 21, 2015

One hundred and seventy-five guests attended the annual Bal du Printemps Galapresented by the Parkinson’s Disease Foundation (PDF) at The Metropolitan Club in New York City on Tuesday, May 19, 2015 for an intimate and important evening.Willie Geist, co-anchor of NBC News’ “Today” and co-host of MSNBC’s “Morning Joe,” served as the Master of Ceremonies for the evening.

Parkinson’s Disease Foundation Announces New Members of People with Parkinson’s Advisory Council
Tuesday, May 12, 2015

The Parkinson’s Disease Foundation® (PDF®) is pleased to announce new members of its People with Parkinson’s Advisory Council. The council is made up of people living with Parkinson’s disease and care partners who help drive PDF’s goals of ending the disease and supporting those affected by it.

The National Parkinson Foundation Welcomes Two New Board Members
Monday, April 6, 2015

MIAMI,FL — The National Parkinson Foundation (NPF) announced the election of two new members to its Board of Directors: Gregory E. Katz and Jonathan Levin.

Rasheda Ali Joins Moving Day® Tampa
Monday, March 16, 2015

Rasheda Ali Joins Tampa Bay Residents to Get "Moving" for Parkinson's Disease

The National Parkinson Foundation Invests in the Future of Parkinson's Research
Monday, March 2, 2015

Support Provided for the Next Generation of Movement Disorder Neurologists

The National Parkinson Foundation Welcomes New Board Member
Wednesday, February 18, 2015

MIAMI, FL — The National Parkinson Foundation (NPF) announced the election of Ricardo Caporal to its Board of Directors. 

National Parkinson Foundation Expands Expert Care Network
Wednesday, February 11, 2015

UC San Diego Health System Designated Center of Excellence 

Erin Borger and Paul Blom Join NPF's Board of Directors
Tuesday, January 13, 2015

MIAMI,FL — The National Parkinson Foundation (NPF) announced the election of two new members to its Board of Directors: Erin R. Borger and Paul R. Blom. 

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