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FDA Approves Revolutionary Parkinson's Treatment and NPF Is Helping Deliver it to You

The National Parkinson Foundation (NPF) is pleased to share that the U.S. Food and Drug Administration (FDA) has approved DUOPA™, developed by AbbVie Inc., as a treatment for people with advanced Parkinson's disease. DUOPA™ is a new approach to the delivery of carbidopa A medication used together with levodopa to enhance its effects. When carbidopa is added to levodopa, the dose of levodopa you take can be smaller while still getting the same benefits, with fewer side effects. and levodopaThe medication most commonly given to control the movement symptoms of Parkinson’s, usually with carbidopa. It is converted in the brain into dopamine. for the treatment of the motor symptoms of Parkinson's disease; it is administered using a small, portable infusion pump that delivers carbidopa and levodopa directly into the small intestine.

Key Highlights about DUOPA™:

  • DUOPA™ is the first and only treatment providing 16 continuous hours of carbidopa and levodopa for motor symptoms in advanced PD.
  • In a clinical trial A research study in humans that aims to test a new intervention – this could be a drug, surgery or therapy like exercise or diet guidelines – to make sure it is effective and safe., patients treated with DUOPA™ experienced significantly greater improvement in “off” time When medication is not working well. Symptoms become more noticeable and movement becomes more difficult. than patients treated with oral carbidopa-levodopa immediate release tablets.

"The approval of the dopamine A chemical messenger (neurotransmitter) that regulates movement and emotions. pump for the treatment of Parkinson's disease is a huge step forward for treatment of Parkinson's disease patients suffering from motor fluctuations Changes in the ability to move, often related to medication timing; also called “on-off” fluctuations. and other disabling symptoms.,"said Dr. Michael S. Okun, NPF's National Medical Director. "We are very enthusiastic about this advance being made available to patients all over the United States."

"Due to the progressive nature of Parkinson's disease, it can be difficult to treat over time, especially in the advanced stages," said Joyce Oberdorf, NPF's President and CEO. "Our organization is encouraged by the introduction of a new therapy that may provide another treatment option for affected patients and families."

NPF is collaborating with AbbVie in the development and delivery of comprehensive training programs on DUOPA™ for NPF Centers of Excellence (COEs). NPF considers AbbVie's DUOPA™ product to be an important tool to address unmet clinical needs for advanced Parkinson’s patients. The one-day trainings will be held in the first quarter of 2015 to ensure COEs are among the first sites to be trained. The trainings will include hands-on sessions to provide a strong foundation for key stakeholders involved in managing treatment with DUOPA™.

This news comes on the heels of last week's FDA approval of RYTARY™ (carbidopa and levodopa) extended-release capsules. If you have questions about either of these newly-approved Parkinson's treatments, NPF's Helpline is available at 1-800-4PD-INFO (1-800-473-4636) or helpline@parkinson.org.

Monday, January 12, 2015
Parkinson's Foundation Hosts National Forum for Women Living with Parkinson's Disease
Wednesday, November 7, 2018

MIAMI & NEW YORK — NOVEMBER 7, 2018 —The Parkinson’s Foundation hosted the first national forum for women with Parkinson’s disease (PD) on October 19 at Baylor College of Medicine, a Parkinson’s Foundation Center of Excellence, in Houston, TX.

Parkinson's Foundation Announces Expansion of Community Grants Program to Address Unmet Community Needs
Thursday, November 1, 2018

The Parkinson’s Foundation is requesting applications for community grants to be awarded nationwide for health, wellness and education programs that address unmet needs in the PD community. The Foundation will award $1.2 million in community grants in 2019.

Parkinson’s Foundation Announces Expansion of Community Grants Program to Address Unmet Community Needs
Thursday, November 1, 2018

NEW YORK & MIAMI — November 1, 2018 — The Parkinson’s Foundation is proud to announce that it is requesting applications for community grants to be awarded nationwide for health, wellness and education programs that address unmet needs in the Parkinson’s disease (PD) community. In 2019, the Parkinson’s Foundation will award $1.2 million in community grants.

Parkinson’s Foundation Hosts Free Bilingual Caregiver Summit
Tuesday, October 30, 2018

MIAMI AND NEW YORK—October 30, 2018—The Parkinson’s Foundation will host a Caregiver Summit – “Cumbre Para Cuidadores” – geared specifically toward caregivers of people living with Parkinson’s disease (PD).

Parkinson’s Foundation Adds James Monhart to its Board of Directors
Monday, October 29, 2018

NEW YORK & MIAMI, October 29, 2018—The Parkinson’s Foundation today announced the election of James F.T. Monhart to its board of directors.

Parkinson’s Foundation Earns 4-Star Rating from Charity Navigator
Monday, October 22, 2018

NEW YORK AND MIAMI—October 22, 2018—The Parkinson’s Foundation has achieved a 4-star rating from Charity Navigator, the nation's largest and most-utilized evaluator of charities.

The 4-star rating is the highest rating given only to nonprofit organizations that exceed industry standards and outperform peers, while demonstrating strong financial health and commitment to accountability and transparency.

Parkinson’s Foundation Awards New Nurse Faculty Grant to Four Nurses Specializing in Parkinson’s Care
Thursday, October 11, 2018

NEW YORK & MIAMI — October 11, 2018 — The Parkinson’s Foundation announced that it has awarded its first-ever Parkinson’s Foundation Nurse Faculty Award to four nurses, totaling $30,000. The nurses, all graduates of the Edmond J.

Update on NUPLAZID — FDA finds no new or unexpected safety risks
Friday, September 21, 2018

On September 20, 2018, the U.S.

Parkinson’s Foundation Extends Bilingual National Helpline Hours
Tuesday, September 18, 2018

NEW YORK & MIAMI — September 18, 2018 — The Parkinson’s Foundation announced today that its toll-free Helpline, 1-800-4PD-INFO, will extend its hours, answering calls in English and Spanish, to help make life better for people with Parkinson’s disease (PD) and their families.

Parkinson’s Foundation Hosts Allied Team Training for Parkinson’s in Atlanta
Tuesday, September 11, 2018

NEW YORK & MIAMI—September 11, 2018—The Parkinson’s Foundation today announced the location of its signature professional education program course, Allied Team Training for Parkinson’s, ATTP®, for health care professionals treating patients with Parkinson’s disease, in Atlanta.

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